6UVG
Crystal structure of BCL-XL bound to compound 13: (R)-2-(3-([1,1'-Biphenyl]-4-carbonyl)-3-(4-methylbenzyl)ureido)-3-(((3R,5R,7R)-adamantan-1-ylmethyl)sulfonyl)propanoic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Bcl-2-like protein 1 | polymer | 158 | 17918.0 | 12 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB | Homo sapiens (Human) | Bcl2-L-1,Apoptosis regulator Bcl-X |
2 | H, I, J, K, L... | (R)-2-(3-([1,1'-Biphenyl]-4-carbonyl)-3-(4-methylbenzyl)ureido)-3-(((3R,5R,7R)-adamantan-1-ylmethyl)sulfonyl)propanoic acid | non-polymer | 628.8 | 12 | Chemie (QHP) | |||
3 | H, J, K, L, A... | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
4 | G, H, A, E | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
5 | water | water | 18.0 | 160 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 26 (UniProt: Q07817)
A, B, C, D, E, F, G, H, I, J, K, L: 83 - 209 (UniProt: Q07817)
PDB | External Database | Details |
---|---|---|
Gly -5 | - | expression tag |
Pro -4 | - | expression tag |
Leu -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 215015.5 | |
Non-Polymers* | Number of molecules | 25 |
Total formula weight | 8624.2 | |
All* | Total formula weight | 223639.7 |