6UUJ

Structure of PE5-PPE4-EspG3 complex from the type VII (ESX-3) secretion system, space group P212121

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G, J (A, D, G, J)	PE family immunomodulator PE5	polymer	100	9228.2	4	UniProt (L7N695) Pfam (PF00934)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
2	B, E, H, K (B, E, H, K)	PPE family protein PPE4	polymer	178	18099.5	4	UniProt (P9WI43) Pfam (PF00823)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
3	C, F, I, L (C, F, I, L)	ESX-3 secretion-associated protein EspG3	polymer	288	30875.9	4	UniProt (B2HNX0) Pfam (PF14011)	Mycobacterium marinum (strain ATCC BAA-535 / M)
4	M, N, O, P (G, H, I, J)	water	water		18.0	4	Chemie (HOH)

Sequence modifications

A, D, G, J: 6 - 102 (UniProt: L7N695)

PDB	External Database	Details
Gly 3	-	expression tag
Ala 4	-	expression tag
Met 5	-	expression tag

C, F, I, L: 5 - 290 (UniProt: B2HNX0)

PDB	External Database	Details
Met 3	-	initiating methionine
Ala 4	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	232814.1
All*	Total formula weight	232814.1

*Water molecules are not included.