6UTH
Allosteric coupling between alpha-rings of 20S proteasome, 20S proteasome singly capped with a PA26/E102A_PANc, together with LFP incubation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Proteasome subunit alpha | polymer | 227 | 25067.5 | 7 | UniProt (P25156) Pfam (PF10584) Pfam (PF00227) In PDB | Thermoplasma acidophilum | 20S proteasome alpha subunit,Proteasome core protein PsmA |
2 | Z, M, 1, N, 2... | Proteasome subunit beta | polymer | 203 | 22294.8 | 14 | UniProt (P28061) Pfam (PF00227) In PDB | Thermoplasma acidophilum | 20S proteasome subunit B, 20S proteasome beta subunit, Proteasome core protein PsmB |
3 | O, P, Q, R, S... | Proteasome subunit alpha | polymer | 227 | 25125.6 | 7 | UniProt (P25156) Pfam (PF10584) Pfam (PF00227) In PDB | Thermoplasma acidophilum | 20S proteasome alpha subunit,Proteasome core protein PsmA |
4 | a, b, c, d, e... | Proteasome activator protein PA26 | polymer | 229 | 25088.6 | 7 | UniProt (Q38BM8) Pfam (PF02252) In PDB | Trypanosoma brucei brucei |
Sequence modifications
A, B, C, D, E, F, G: 7 - 233 (UniProt: P25156)
a, b, c, d, e, f, g: 4 - 223 (UniProt: Q38BM8)
PDB | External Database | Details |
---|---|---|
Ala 66 | Lys 66 | conflict |
PDB | External Database | Details |
---|---|---|
Gly 48 | Ala 48 | conflict |
Ala 102 | Glu 102 | conflict |
Gly 224 | - | expression tag |
Gly 225 | - | expression tag |
His 226 | - | expression tag |
Leu 227 | - | expression tag |
Asp 228 | - | expression tag |
Val 229 | - | expression tag |
Leu 230 | - | expression tag |
Tyr 231 | - | expression tag |
Arg 232 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 35 |
Total formula weight | 839099.9 | |
All* | Total formula weight | 839099.9 |