6USJ
Structure of two nucleosomes bridged by human PARP2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | I, S | Widom 601 DNA (160-MER) | polymer | 165 | 51141.6 | 2 | synthetic construct | ||
2 | J, T | Widom 601 DNA (160-MER) | polymer | 165 | 50732.3 | 2 | synthetic construct | ||
3 | A, E, K, O | Histone H3.1 | polymer | 139 | 15719.4 | 4 | UniProt (P68431) Pfam (PF00125) In PDB | Homo sapiens (Human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
4 | B, F, L, P | Histone H4 | polymer | 106 | 11676.7 | 4 | UniProt (P62805) Pfam (PF15511) In PDB | Homo sapiens (Human) | |
5 | C, G, M, Q | Histone H2A | polymer | 133 | 14447.8 | 4 | UniProt (Q08AJ9) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P04908) In PDB | Homo sapiens (Human) | |
6 | D, H, N, R | Histone H2B type 1-J | polymer | 129 | 14217.5 | 4 | UniProt (P06899) Pfam (PF00125) In PDB | Homo sapiens (Human) | Histone H2B.1,Histone H2B.r,H2B/r |
7 | U, V | Poly [ADP-ribose] polymerase 2 | polymer | 590 | 67069.5 | 2 | UniProt (Q9UGN5) Pfam (PF05406) Pfam (PF02877) Pfam (PF00644) In PDB | Homo sapiens (Human) | hPARP-2,ADP-ribosyltransferase diphtheria toxin-like 2,ARTD2,DNA ADP-ribosyltransferase PARP2,NAD(+) ADP-ribosyltransferase 2,ADPRT-2,Poly[ADP-ribose] synthase 2,pADPRT-2,Protein poly-ADP-ribosyltransferase PARP2 |
Sequence modifications
A, E, K, O: 0 - 135 (UniProt: P68431)
B, F, L, P: 0 - 102 (UniProt: P62805)
C, G, M, Q: 0 - 129 (UniProt: Q08AJ9)
D, H, N, R: 0 - 125 (UniProt: P06899)
U, V: 1 - 570 (UniProt: Q9UGN5)
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met -19 | - | expression tag |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Arg 112 | Gln 112 | engineered mutation |
Asp 113 | Phe 113 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 22 |
Total formula weight | 562132.6 | |
All* | Total formula weight | 562132.6 |