6UQG

Human HCN1 channel Y289D mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1	polymer	660	74595.6	4	UniProt (O60741) Pfam (PF08412) Pfam (PF00520) Pfam (PF00027)	Homo sapiens (Human)	Brain cyclic nucleotide-gated channel 1,BCNG-1
2	E, F, G, H (A, B, C, D)	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE	non-polymer		329.2	4	Chemie (CMP)

Sequence modifications

A, B, C, D: 1 - 635 (UniProt: O60741)

PDB	External Database	Details
Asp 289	Tyr 289	engineered mutation

A, B, C, D: 866 - 890 (UniProt: O60741)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	298382.6
Non-Polymers*	Number of molecules	4
	Total formula weight	1316.8
All*	Total formula weight	299699.4

*Water molecules are not included.