6UQF
Human HCN1 channel in a hyperpolarized conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | polymer | 660 | 74615.8 | 4 | UniProt (O60741) Pfam (PF08412) Pfam (PF00520) Pfam (PF00027) | Homo sapiens (Human) | Brain cyclic nucleotide-gated channel 1,BCNG-1 |
| 2 | E, G, I, K (A, B, C, D) | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 4 | Chemie (CMP) | |||
| 3 | F, H, J, L (A, B, C, D) | MERCURY (II) ION | non-polymer | 200.6 | 4 | Chemie (HG) |
Sequence modifications
A, B, C, D: 1 - 635 (UniProt: O60741)
A, B, C, D: 866 - 890 (UniProt: O60741)
| PDB | External Database | Details |
|---|---|---|
| Cys 186 | Phe 186 | conflict |
| Cys 264 | Ser 264 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 298463.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2119.2 | |
| All* | Total formula weight | 300582.2 |
