6UQF

Human HCN1 channel in a hyperpolarized conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1	polymer	660	74615.8	4	UniProt (O60741) Pfam (PF08412) Pfam (PF00520) Pfam (PF00027) In PDB	Homo sapiens (Human)	Brain cyclic nucleotide-gated channel 1,BCNG-1
2	A, B, C, D	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE	non-polymer		329.2	4	Chemie (CMP)
3	A, B, C, D	MERCURY (II) ION	non-polymer		200.6	4	Chemie (HG)

Sequence modifications

A, B, C, D: 1 - 635 (UniProt: O60741)

PDB	External Database	Details
Cys 186	Phe 186	conflict
Cys 264	Ser 264	conflict

A, B, C, D: 866 - 890 (UniProt: O60741)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	298463.1
Non-Polymers*	Number of molecules	8
	Total formula weight	2119.2
All*	Total formula weight	300582.2

*Water molecules are not included.