6UP7
neurotensin receptor and arrestin2 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | ARG-ARG-PRO-TYR-ILE-LEU | polymer | 6 | 819.0 | 1 | UniProt (by SIFTS) (P30990) | Homo sapiens (Human) | |
| 2 | B (B) | Beta-arrestin-1 | polymer | 348 | 39062.8 | 1 | UniProt (P49407) Pfam (PF00339) Pfam (PF02752) | Homo sapiens (Human) | Arrestin beta-1,Non-visual arrestin-2 |
| 3 | C (R) | Neurotensin receptor type 1 | polymer | 334 | 37360.7 | 1 | UniProt (P30989) Pfam (PF00001) | Homo sapiens (Human) | NTR1,High-affinity levocabastine-insensitive neurotensin receptor,NTRH |
| 4 | D (V) | unidentified peptide | polymer | 9 | 784.0 | 1 | Homo sapiens | ||
| 5 | E (R) | [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | non-polymer | 746.6 | 1 | Chemie (PIO) |
Sequence modifications
B: 8 - 355 (UniProt: P49407)
| PDB | External Database | Details |
|---|---|---|
| Val 59 | Cys 59 | engineered mutation |
| Ser 125 | Cys 125 | engineered mutation |
| Leu 140 | Cys 140 | engineered mutation |
| Val 150 | Cys 150 | engineered mutation |
| Val 242 | Cys 242 | engineered mutation |
| Val 251 | Cys 251 | engineered mutation |
| Ser 269 | Cys 269 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 78026.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 746.6 | |
| All* | Total formula weight | 78773.0 |
