6UO2
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 1 (CD1) complexed with Trichostatin A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HDAC6 | polymer | 366 | 40294.6 | 2 | UniProt (F8W4B7) Pfam (PF00850) | Danio rerio (Zebrafish) | |
| 2 | C, G (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, E, H, I (A, B) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 4 | F, J (A, B) | TRICHOSTATIN A | non-polymer | 302.4 | 2 | Chemie (TSN) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 193 | Chemie (HOH) |
Sequence modifications
A, B: 60 - 419 (UniProt: F8W4B7)
| PDB | External Database | Details |
|---|---|---|
| Ser 54 | - | expression tag |
| Asn 55 | - | expression tag |
| Ala 56 | - | expression tag |
| Gly 57 | - | expression tag |
| Gly 58 | - | expression tag |
| Ser 59 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 80589.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 891.9 | |
| All* | Total formula weight | 81481.1 |
