6UNZ

Crystal structure of cytosolic fumarate hydratase from Leishmania major

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	fumarate hydratase 2	polymer	604	66513.5	8	UniProt (E9AE57) Pfam (PF05681) Pfam (PF05683) In PDB	Leishmania major strain Friedlin
2	A, B, C, D, E...	IRON/SULFUR CLUSTER	non-polymer		351.6	8	Chemie (SF4)
3	B, E	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4		water	water		18.0	3	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 568 (UniProt: E9AE57)

PDB	External Database	Details
Met -35	-	expression tag
Gly -34	-	expression tag
Ser -33	-	expression tag
Ser -32	-	expression tag
His -31	-	expression tag
His -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
Ser -25	-	expression tag
Ser -24	-	expression tag
Gly -23	-	expression tag
Leu -22	-	expression tag
Val -21	-	expression tag
Pro -20	-	expression tag
Arg -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
Met -15	-	expression tag
Ala -14	-	expression tag
Ser -13	-	expression tag
Met -12	-	expression tag
Thr -11	-	expression tag
Gly -10	-	expression tag
Gly -9	-	expression tag
Gln -8	-	expression tag
Gln -7	-	expression tag
Met -6	-	expression tag
Gly -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	532107.8
Non-Polymers*	Number of molecules	10
	Total formula weight	2997.3
All*	Total formula weight	535105.1

*Water molecules are not included.