6UMD

Crystal structure of human GAC in complex with inhibitor UPGL00012

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Glutaminase kidney isoform, mitochondrial	polymer	527	58052.0	4	UniProt (O94925) Pfam (PF17959) Pfam (PF04960) In PDB	Homo sapiens (Human)	GLS,K-glutaminase,L-glutamine amidohydrolase
2	B, D	2-(pyridin-3-yl)-N-(5-{4-[(5-{[(pyridin-3-yl)acetyl]amino}-1,3,4-thiadiazol-2-yl)amino]piperidin-1-yl}-1,3,4-thiadiazol-2-yl)acetamide	non-polymer		536.6	2	Chemie (QAJ)
3		water	water		18.0	42	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	232208.2
Non-Polymers*	Number of molecules	2
	Total formula weight	1073.3
All*	Total formula weight	233281.4

*Water molecules are not included.