6ULK
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I antigen | polymer | 274 | 31837.1 | 1 | UniProt (C1K0Y1) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (Human) | MHC class I antigen,MHC class I histocompatibility antigen |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C (C) | GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA-LEU | polymer | 10 | 875.0 | 1 | UniProt (P01111) | Homo sapiens | |
| 4 | D, E, F (A, B, C) | water | water | 18.0 | 148 | Chemie (HOH) |
Sequence modifications
B: 1 - 99 (UniProt: P61769)
C: 1 - 10 (UniProt: P01111)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Asp 3 | Gly 12 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44591.4 | |
| All* | Total formula weight | 44591.4 |
