6UL7

Structure of human ketohexokinase-C in complex with fructose, NO3, and osthole

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Ketohexokinase	polymer	318	34733.3	1	UniProt (P50053) Pfam (PF00294) In PDB	Homo sapiens (Human)	Hepatic fructokinase, Ketohexokinase-C
2	A	beta-D-fructofuranose	non-polymer		180.2	1	Chemie (FRU)
3	A	7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one	non-polymer		244.3	1	Chemie (A0O)
4	A	NITRATE ION	non-polymer		62.0	1	Chemie (NO3)
5		water	water		18.0	199	Chemie (HOH)

Sequence modifications

A: 1 - 298 (UniProt: P50053)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34733.3
Non-Polymers*	Number of molecules	3
	Total formula weight	486.4
All*	Total formula weight	35219.8

*Water molecules are not included.