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6UKN

Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Solute carrier family 12 member 7polymer1092120611.01UniProt (Q9WVL3)
Pfam (PF00324)
Pfam (PF03522)
Mus musculus (Mouse)Electroneutral potassium-chloride cotransporter 4,K-Cl cotransporter 4
2B, C
(B, C)
beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.52In PDB
GlyTouCan (G15407YE)
3D
(A)
POTASSIUM IONnon-polymer39.11Chemie (K)
4E
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
Sequence modifications
A: 1 - 1083 (UniProt: Q9WVL3)
PDBExternal DatabaseDetails
Ser 1084-expression tag
Asn 1085-expression tag
Ser 1086-expression tag
Leu 1087-expression tag
Glu 1088-expression tag
Val 1089-expression tag
Leu 1090-expression tag
Phe 1091-expression tag
Gln 1092-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight120611.0
BranchedNumber of molecules2
Total formula weight1173.1
Non-Polymers*Number of molecules2
Total formula weight74.6
All*Total formula weight121858.6
*Water molecules are not included.

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PDB entries from 2026-02-25

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