6UJP
P-glycoprotein mutant-F979A and C952A-with BDE100
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | ATP-dependent translocase ABCB1 | polymer | 1282 | 141569.5 | 1 | UniProt (P21447) Pfam (PF00664) Pfam (PF00005) In PDB | Mus musculus (Mouse) | ATP-binding cassette sub-family B member 1A,MDR1A,Multidrug resistance protein 1A,Multidrug resistance protein 3,P-glycoprotein 3,Phospholipid transporter ABCB1 |
2 | A | 2,4-dibromophenyl 2,4,6-tribromophenyl ether | non-polymer | 564.7 | 1 | Chemie (4C8) |
Sequence modifications
A: 1 - 1276 (UniProt: P21447)
PDB | External Database | Details |
---|---|---|
Gln 83 | Asn 83 | engineered mutation |
Gln 87 | Asn 87 | engineered mutation |
Gln 90 | Asn 90 | engineered mutation |
Ala 952 | Cys 952 | engineered mutation |
Ala 979 | Phe 979 | engineered mutation |
His 1277 | - | expression tag |
His 1278 | - | expression tag |
His 1279 | - | expression tag |
His 1280 | - | expression tag |
His 1281 | - | expression tag |
His 1282 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 141569.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 564.7 | |
All* | Total formula weight | 142134.2 |