6UJK
Crystal Structure of a Probable short-chain type dehydrogenase/reductase (Rv1144) from Mycobacterium tuberculosis with bound NAD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Uncharacterized oxidoreductase Rv1144 | polymer | 258 | 26845.9 | 2 | UniProt (P9WGQ7) Pfam (PF00106) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | MytuD.00554.a.B1 |
| 2 | C, H (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 3 | D, E, F, I, J... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 4 | G (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 5 | M, N (A, B) | water | water | 18.0 | 519 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 250 (UniProt: P9WGQ7)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| Ala -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53691.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1883.5 | |
| All* | Total formula weight | 55575.2 |
