6UJH
Discovery of fragment-inspired heterocyclic benzenesulfonamides as inhibitors of the WDR5-MYC interaction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | WD repeat-containing protein 5 | polymer | 313 | 34391.0 | 2 | UniProt (P61964) Pfam (PF00400) | Homo sapiens (Human) | BMP2-induced 3-kb gene protein |
| 2 | C, F (A, B) | (2R)-2-(4-chlorophenyl)-3-oxobutanenitrile | non-polymer | 193.6 | 2 | Chemie (QBS) | |||
| 3 | D, E, G (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | H, I, J (B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 919 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68782.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 909.8 | |
| All* | Total formula weight | 69691.8 |
