6UJG
Crystal structure of human GAC in complex with inhibitor UPGL00012
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Glutaminase kidney isoform, mitochondrial | polymer | 527 | 58024.0 | 8 | UniProt (O94925) Pfam (PF17959) Pfam (PF04960) In PDB | Homo sapiens (Human) | GLS,K-glutaminase,L-glutamine amidohydrolase |
| 2 | C, D, E, F | N-{5-[(3S)-3-{[5-(acetylamino)-1,3,4-thiadiazol-2-yl]amino}pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide | non-polymer | 368.4 | 4 | Chemie (Q9A) |
Sequence modifications
A, B, C, D, E, F, G, H: 72 - 598 (UniProt: O94925)
| PDB | External Database | Details |
|---|---|---|
| Ala 268 | Val 268 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 464192.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1473.8 | |
| All* | Total formula weight | 465665.7 |
