6UIW
Cryo-EM structure of human CALHM2 in a ruthenium red-bound inhibited state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Calcium homeostasis modulator protein 2 | polymer | 331 | 37198.7 | 11 | UniProt (Q9HA72) Pfam (PF14798) | Homo sapiens (Human) | Protein FAM26B |
| 2 | L, M, N, O, P... (A, B, C, D, E...) | ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2) | non-polymer | 559.5 | 11 | Chemie (R2R) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K: 1 - 323 (UniProt: Q9HA72)
| PDB | External Database | Details |
|---|---|---|
| Phe 324 | - | expression tag |
| Glu 325 | - | expression tag |
| Ser 326 | - | expression tag |
| Arg 327 | - | expression tag |
| Leu 328 | - | expression tag |
| Val 329 | - | expression tag |
| Pro 330 | - | expression tag |
| Arg 331 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 409185.4 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 6154.8 | |
| All* | Total formula weight | 415340.2 |
