6UIK
Discovery of fragment-inspired heterocyclic benzenesulfonmides as inhibitors of the WDR5-MYC interaction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | WD repeat domanin 5 | polymer | 304 | 33492.0 | 2 | UniProt (P61964) Pfam (PF00400) | Homo sapiens | |
| 2 | C, D (A, B) | 5-bromo-3-chloro-N-(1-cyclopentyl-1H-imidazol-4-yl)-2-hydroxybenzene-1-sulfonamide | non-polymer | 420.7 | 2 | Chemie (Q8M) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 788 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66984.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 841.4 | |
| All* | Total formula weight | 67825.5 |
