6UIF

Discovery of fragment-inspired heterocyclic benzenesulfonmides as inhibitors of the WDR5-MYC interaction

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	WD repeat domain 5	polymer	304	33492.0	2	UniProt (P61964) Pfam (PF00400) In PDB	Homo sapiens
2	A, B	4-{[(5-bromo-3-chloro-2-hydroxyphenyl)sulfonyl]amino}-1-cyclopentyl-N-methyl-1H-imidazole-2-carboxamide	non-polymer		477.8	2	Chemie (Q8P)
3		water	water		18.0	603	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66984.0
Non-Polymers*	Number of molecules	2
	Total formula weight	955.5
All*	Total formula weight	67939.6

*Water molecules are not included.