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6UGY

Crystal structure of the Fc fragment of anti-TNFa antibody infliximab (Remicade) in a primative orthorhombic crystal form, Lot C

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ARemicade Fcpolymer25528361.31UniProt (P0DOX5)
Pfam (PF07654)
In PDB
Homo sapiens (Human)Immunoglobulin gamma-1 heavy chain NIE
2Bbeta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranosebranched1422.31In PDB
GlyTouCan (G61334IA)
3AZINC IONnon-polymer65.43Chemie (ZN)
4AACETATE IONnon-polymer59.01Chemie (ACT)
5waterwater18.0140Chemie (HOH)
Sequence modifications
A: 196 - 220 (PDB: 6UGY)
A: 221 - 450 (UniProt: P0DOX5)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28361.3
BranchedNumber of molecules1
Total formula weight1422.3
Non-Polymers*Number of molecules4
Total formula weight255.3
All*Total formula weight30038.8
*Water molecules are not included.

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PDB entries from 2024-05-29

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