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6UGS

Crystal structure of the Fab fragment of PF06438179/GP1111 an infliximab biosimilar in a C-centered orthorhombic crystal form, Lot A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1H, AInfliximab (Remicade) Fab Heavy Chainpolymer22624356.22UniProt (A8K008)
Pfam (PF07686)
Pfam (PF07654)
In PDB
Homo sapiens (Human)
2L, BInfliximab (Remicade) Fab Light Chainpolymer21423460.92UniProt (Q6P5S8)
Pfam (PF07686)
Pfam (PF07654)
In PDB
Homo sapiens (Human)
3waterwater18.01047Chemie (HOH)
Sequence modifications
H, A: 1 - 116 (PDB: 6UGS)
H, A: 117 - 226 (UniProt: A8K008)
L, B: 1 - 106 (PDB: 6UGS)
L, B: 107 - 214 (UniProt: Q6P5S8)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight95634.1
All*Total formula weight95634.1
*Water molecules are not included.

223532

PDB entries from 2024-08-07

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