6UDV
X-ray co-crystal structure of compound 3 bound to human Mcl-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 157 | 17922.3 | 1 | UniProt (Q07820) Pfam (PF00452) | Homo sapiens (Human) | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | B (A) | (4S,7aR,9aR,10S,11E,14S,15R)-6'-chloro-10-hydroxy-14,15-dimethyl-3',4',7a,8,9,9a,10,13,14,15-decahydro-2'H,3H,5H-spiro[1,19-(ethanediylidene)-16lambda~6~-cyclobuta[i][1,4]oxazepino[3,4-f][1,2,7]thiadiazacyclohexadecine-4,1'-naphthalene]-16,16,18(7H,17H)-trione | non-polymer | 599.2 | 1 | Chemie (Q51) PubChem (118910323) PubChem (118910215) PubChem (118910254) PubChem (118910326) PubChem (118910329) PubChem (140926782) PubChem (161380906) PubChem (140926762) PubChem (140926791) PubChem (153499343) PubChem (162456233) PubChem (163384318) PubChem (166832009) PubChem (168141394) PubChem (168771382) PubChem (171360911) PubChem (175725443) PubChem (175815282) PubChem (175934802) | |||
| 3 | C (A) | water | water | 18.0 | 156 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17922.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 599.2 | |
| All* | Total formula weight | 18521.5 |
