6UDU
X-ray co-crystal structure of compound 8 bound to human Mcl-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 157 | 17922.3 | 1 | UniProt (Q07820) Pfam (PF00452) In PDB | Homo sapiens (Human) | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | A | (4S,11E,17R)-6'-chloro-17-hydroxy-14-methyl-15-oxo-3',4',8,9,10,13,14,15,16,17-decahydro-2'H,3H,5H,7H-spiro[1,18-(ethanediylidene)[1,4]oxazepino[4,3-a][1,8]diazacyclopentadecine-4,1'-naphthalene]-17-carboxylic acid | non-polymer | 539.1 | 1 | Chemie (Q4Y) | |||
| 3 | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17922.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 539.1 | |
| All* | Total formula weight | 18461.4 |
