6UD3

Full length Glycine receptor reconstituted in lipid nanodisc in Gly/PTX-bound open/blocked conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E (A, C, E, D, B)	Glycine receptor subunit alphaZ1	polymer	459	52594.6	5	UniProt (O93430) Pfam (PF02931) Pfam (PF02932)	Danio rerio (Zebrafish)
2	F, I, K, N, P (A, C, E, D, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)
3	G, J, L, M, O (A, C, E, D, B)	GLYCINE	non-polymer		75.1	5	Chemie (GLY)
4	H (A)	(1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione	non-polymer		292.3	1	Chemie (RI5)

Sequence modifications

A, C, E, D, B: 1 - 444 (UniProt: O93430)

PDB	External Database	Details
Gly 445	-	expression tag
Leu 446	-	expression tag
Val 447	-	expression tag
Pro 448	-	expression tag
Arg 449	-	expression tag
Gly 450	-	expression tag
Ser 451	-	expression tag
His 452	-	expression tag
His 453	-	expression tag
His 454	-	expression tag
His 455	-	expression tag
His 456	-	expression tag
His 457	-	expression tag
His 458	-	expression tag
His 459	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	262973.2
Non-Polymers*	Number of molecules	11
	Total formula weight	1773.7
All*	Total formula weight	264746.9

*Water molecules are not included.