6UA2
Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Bent (2/4 compressed, 2/4 extended) segment reconstruction.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, M...) | Inosine-5'-monophosphate dehydrogenase 2 | polymer | 519 | 56480.5 | 16 | UniProt (P12268) Pfam (PF00478) Pfam (PF00571) | Homo sapiens (Human) | IMPDH 2,IMPDH-II |
| 2 | IA, JA, NA, OA, Q... (E, F, A, B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 8 | Chemie (GTP) | |||
| 3 | AA, BA, EA, FA, KA... (C, D, E, F, A...) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 12 | Chemie (ATP) | |||
| 4 | CA, GA, LA, QA, T... (C, D, E, F, A...) | INOSINIC ACID | non-polymer | 348.2 | 8 | Chemie (IMP) | |||
| 5 | DA, HA, MA, RA, U... (C, D, E, F, A...) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 8 | Chemie (NAD) |
Sequence modifications
A, B, C, D, M, N, O, P, E, F, G, H, I, J, K, L: 1 - 514 (UniProt: P12268)
| PDB | External Database | Details |
|---|---|---|
| Ser -4 | - | expression tag |
| Glu -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Leu 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 903688.0 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 18364.7 | |
| All* | Total formula weight | 922052.7 |
