6U91
Crystal structure of DNMT3B(Q772R)-DNMT3L in complex with CpGpT DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D | DNA (cytosine-5)-methyltransferase 3B | polymer | 291 | 33215.5 | 2 | UniProt (Q9UBC3) Pfam (PF00145) In PDB | Homo sapiens (Human) | Dnmt3b,DNA methyltransferase HsaIIIB,M.HsaIIIB |
| 2 | B, C | DNA (cytosine-5)-methyltransferase 3-like | polymer | 209 | 24163.7 | 2 | UniProt (Q9UJW3) In PDB | Homo sapiens (Human) | |
| 3 | E, F | CpGpT DNA (25-MER) | polymer | 25 | 7699.0 | 2 | Homo sapiens | ||
| 4 | A, D | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | A, D | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 6 | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A, D: 563 - 853 (UniProt: Q9UBC3)
| PDB | External Database | Details |
|---|---|---|
| Arg 772 | Gln 772 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 130156.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 841.7 | |
| All* | Total formula weight | 130998.0 |
