6U8O
Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | WD repeat-containing protein 5 | polymer | 304 | 33492.0 | 1 | UniProt (P61964) Pfam (PF00400) | Homo sapiens (Human) | BMP2-induced 3-kb gene protein |
| 2 | B (A) | 5-bromo-N-[5-(1-cyanocyclobutyl)-2-hydroxyphenyl]-2-hydroxybenzene-1-sulfonamide | non-polymer | 423.3 | 1 | Chemie (Q1G) | |||
| 3 | C (A) | water | water | 18.0 | 371 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33492.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 423.3 | |
| All* | Total formula weight | 33915.3 |
