6U8M

BRD4-BD1 in complex with the cyclic peptide 3.2_1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Bromodomain-containing protein 4	polymer	146	17200.6	2	UniProt (O60885) Pfam (PF00439) In PDB	Homo sapiens (Human)	Protein HUNK1
2	C	cyclic peptide 3.2_1	polymer	18	2075.6	1		synthetic construct
3	C	AMINO GROUP	non-polymer		16.0	1	Chemie (NH2)
4		water	water		18.0	214	Chemie (HOH)

Sequence modifications

A, B: 42 - 168 (UniProt: O60885)

PDB	External Database	Details
Gln 36	-	expression tag
Gly 37	-	expression tag
Pro 38	-	expression tag
Leu 39	-	expression tag
Gly 40	-	expression tag
Ser 41	-	expression tag
Pro 169	-	expression tag
Glu 170	-	expression tag
Phe 171	-	expression tag
Pro 172	-	expression tag
Gly 173	-	expression tag
Arg 174	-	expression tag
Leu 175	-	expression tag
Glu 176	-	expression tag
Arg 177	-	expression tag
Pro 178	-	expression tag
His 179	-	expression tag
Arg 180	-	expression tag
Asp 181	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	36476.9
Non-Polymers*	Number of molecules	1
	Total formula weight	16.0
All*	Total formula weight	36492.9

*Water molecules are not included.