6U6W
Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | WD repeat-containing protein 5 | polymer | 311 | 34232.8 | 2 | UniProt (P61964) Pfam (PF00400) In PDB | Homo sapiens (Human) | BMP2-induced 3-kb gene protein |
2 | A, B | 5-bromo-N-(5-chloro-2-hydroxyphenyl)-2-methoxybenzene-1-sulfonamide | non-polymer | 392.7 | 2 | Chemie (Q0Y) | |||
3 | water | water | 18.0 | 921 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 68465.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 785.3 | |
All* | Total formula weight | 69251.0 |