6U6L
BRD4-BD2 in complex with the cyclic peptide 3.1_2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain-containing protein 4 | polymer | 123 | 14186.3 | 1 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
| 2 | B | Cyclic peptide 3.1_2 | polymer | 15 | 1918.3 | 1 | synthetic construct | ||
| 3 | B | AMINO GROUP | non-polymer | 16.0 | 1 | Chemie (NH2) | |||
| 4 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A: 347 - 464 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Gln 342 | - | expression tag |
| Gly 343 | - | expression tag |
| Pro 344 | - | expression tag |
| Leu 345 | - | expression tag |
| Gly 346 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 16104.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 108.1 | |
| All* | Total formula weight | 16212.7 |
