6U67
Mcl-1 bound to compound 24
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 156 | 17838.2 | 2 | UniProt (Q07820) Pfam (PF00452) | Homo sapiens (Human) | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | C, D, E, G, H... (A, B) | 2-({[4-(4-tert-butylphenyl)piperazin-1-yl]sulfonyl}amino)-5-{[3-oxo-3-(phenylamino)propyl]sulfanyl}benzoic acid | non-polymer | 596.8 | 6 | Chemie (Q01) | |||
| 3 | F, J (A, B) | BIPHENYL | non-polymer | 154.2 | 2 | Chemie (BNL) | |||
| 4 | K, L (A, B) | water | water | 18.0 | 180 | Chemie (HOH) |
Sequence modifications
A, B: 171 - 323 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Ser 168 | - | expression tag |
| Asn 169 | - | expression tag |
| Ala 170 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35676.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3889.0 | |
| All* | Total formula weight | 39565.4 |
