6U5Y
Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | WD repeat-containing protein 5 | polymer | 304 | 33492.0 | 2 | UniProt (P61964) Pfam (PF00400) In PDB | Homo sapiens (Human) | BMP2-induced 3-kb gene protein |
| 2 | A, B | 3-{[(5-bromo-3-chloro-2-hydroxyphenyl)sulfonyl]amino}-5-(1-cyanocyclobutyl)-2-hydroxy-N-methylbenzamide | non-polymer | 514.8 | 2 | Chemie (Q0M) | |||
| 3 | water | water | 18.0 | 802 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66984.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1029.6 | |
| All* | Total formula weight | 68013.6 |
