6TZU
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, N84A mutant with pyruvate bound in the active site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E | 4-hydroxy-tetrahydrodipicolinate synthase | polymer | 310 | 34073.2 | 5 | UniProt (Q9PPB4) Pfam (PF00701) In PDB | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) | HTPA synthase |
| 2 | F | 4-hydroxy-tetrahydrodipicolinate synthase | polymer | 310 | 34142.2 | 1 | UniProt (Q9PPB4) Pfam (PF00701) In PDB | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) | HTPA synthase |
| 3 | F, A, B, E | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 4 | F, D, A, B, E | 1,2-ETHANEDIOL | non-polymer | 62.1 | 24 | Chemie (EDO) | |||
| 5 | C, F, A, E, B | ACETATE ION | non-polymer | 59.0 | 16 | Chemie (ACT) | |||
| 6 | F, A, D, B | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 4 | Chemie (PGE) | |||
| 7 | C, B, E | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 4 | Chemie (PEG) | |||
| 8 | D, E | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 9 | water | water | 18.0 | 1321 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 298 (UniProt: Q9PPB4)
F: 1 - 298 (UniProt: Q9PPB4)
| PDB | External Database | Details |
|---|---|---|
| Met -11 | - | expression tag |
| Arg -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Ser -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 84 | Asn 84 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met -11 | - | expression tag |
| Arg -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Ser -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 84 | Asn 84 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 204508.2 | |
| Non-Polymers* | Number of molecules | 55 |
| Total formula weight | 3765.2 | |
| All* | Total formula weight | 208273.4 |
