6TZB
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin in complex with 6'-SLNLN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E | Hemagglutinin HA1 chain | polymer | 321 | 35320.8 | 3 | UniProt (Q91MA7) Pfam (PF00509) In PDB | Influenza A virus (strain A/Hong Kong/1/1968 H3N2) | |
| 2 | B, D, F | Hemagglutinin HA2 chain | polymer | 176 | 20197.3 | 3 | UniProt (H9XC94) Pfam (PF00509) In PDB | Influenza A virus (strain A/Hong Kong/1/1968 H3N2) | |
| 3 | G, H, L | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 4 | I, N, P | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 5 | J, Q | N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1039.9 | 2 | In PDB GlyTouCan (G60430KO) | |||
| 6 | K | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 7 | M | N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 674.6 | 1 | In PDB BIRD (PRD_900046) GlyTouCan (G73578JC) | 6'-sialyl-N-acetyllactosamine | ||
| 8 | O | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 9 | A, C, D, E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 10 | water | water | 18.0 | 919 | Chemie (HOH) |
Sequence modifications
A, C, E: 11 - 329 (UniProt: Q91MA7)
B, D, F: 1 - 176 (UniProt: H9XC94)
| PDB | External Database | Details |
|---|---|---|
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 123 | Arg 468 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 166554.3 | |
| Branched | Number of molecules | 11 |
| Total formula weight | 7284.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1106.0 | |
| All* | Total formula weight | 174945.0 |
