6TYW
Structure of Ku80 von Willebrand domain S229A mutant complexed with APLF Ku Binding Motif
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | X-ray repair cross-complementing protein 5 | polymer | 231 | 26170.0 | 1 | UniProt (A0A1L8EVE5) Pfam (PF03731) UniProt (by SIFTS) (Q6DDS9) | Xenopus laevis (African clawed frog) | |
| 2 | B (B) | GLU-ARG-LYS-ARG-ILE-LEU-PRO-THR-TRP-MET-LEU-ALA-GLU | polymer | 16 | 1968.4 | 1 | UniProt (by SIFTS) (Q8IW19) | Homo sapiens | |
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 219 | Chemie (HOH) |
Sequence modifications
A: 1 - 242 (UniProt: A0A1L8EVE5)
| PDB | External Database | Details |
|---|---|---|
| Met -6 | - | initiating methionine |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| - | Glu 171 | deletion |
| - | Glu 172 | deletion |
| - | Phe 173 | deletion |
| - | Gly 174 | deletion |
| - | Gly 175 | deletion |
| - | Ser 176 | deletion |
| - | Ser 177 | deletion |
| - | Asn 178 | deletion |
| - | Asn 179 | deletion |
| - | Arg 180 | deletion |
| - | Gly 181 | deletion |
| - | Asn 182 | deletion |
| - | Ala 183 | deletion |
| - | Gly 184 | deletion |
| - | Ser 185 | deletion |
| - | Ser 186 | deletion |
| - | Asp 187 | deletion |
| - | Arg 188 | deletion |
| Ser 190 | Cys 190 | engineered mutation |
| Ala 229 | Ser 229 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28138.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 62.1 | |
| All* | Total formula weight | 28200.4 |
