6TWS

Crystal structure of the haemagglutinin mutant (Gln226Leu, Gly228Ser) from an H10N7 seal influenza virus isolated in Germany with 2mM EDTA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (G, A, C)	Hemagglutinin	polymer	325	35514.1	3	UniProt (A0A0A7HR51)	Influenza A virus (A/harbour seal/Germany/1/2014(H10N7))
2	B, D, F (H, B, D)	Hemagglutinin HA2	polymer	177	20313.4	3	UniProt (A0A0A7HR51)	Influenza A virus (A/harbour seal/Germany/1/2014(H10N7))
3	G, H, I (E, F, I)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
4	AA, BA, CA, DA, EA... (C, D, G, H, A...)	1,2-ETHANEDIOL	non-polymer		62.1	22	Chemie (EDO)
5	U, V (B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
6	HA, IA, JA, KA, LA... (G, H, A, B, C...)	water	water		18.0	1101	Chemie (HOH)

Sequence modifications

G, A, C: 1 - 323 (UniProt: A0A0A7HR51)

PDB	External Database	Details
Asp -1	-	expression tag
Pro 0	-	expression tag
Ser 221	Gly 230	engineered mutation

H, B, D: 1 - 176 (UniProt: A0A0A7HR51)

PDB	External Database	Details
Lys 177	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	167482.6
Branched	Number of molecules	3
	Total formula weight	1273.2
Non-Polymers*	Number of molecules	24
	Total formula weight	1807.9
All*	Total formula weight	170563.7

*Water molecules are not included.