6TWH

Crystal structure of the haemagglutinin mutant (Gln226Leu, Gly228Ser) from an H10N7 seal influenza virus isolated in Germany

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (A, C, E, L, N...)	Hemagglutinin	polymer	325	35514.1	6	UniProt (A0A0A7HR51) Pfam (PF00509)	Influenza A virus (A/harbour seal/Germany/1/2014(H10N7))
2	B, D, F, H, J... (B, D, F, M, O...)	Hemagglutinin HA2	polymer	177	20313.4	6	UniProt (A0A0A7HR51) Pfam (PF00509)	Influenza A virus (A/harbour seal/Germany/1/2014(H10N7))
3	M, N (G, H)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
4	O, Q, R, S, T... (C, F, M, N, O...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG)
5	P, U, X (E, N, P)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
6	AA, BA, CA, DA, EA... (B, C, D, E, F...)	water	water		18.0	81	Chemie (HOH)

Sequence modifications

A, C, E, L, N, P: 1 - 323 (UniProt: A0A0A7HR51)

PDB	External Database	Details
Asp -1	-	expression tag
Pro 0	-	expression tag
Ser 221	Gly 230	engineered mutation

B, D, F, M, O, Q: 1 - 176 (UniProt: A0A0A7HR51)

PDB	External Database	Details
Lys 177	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	334965.2
Branched	Number of molecules	2
	Total formula weight	848.8
Non-Polymers*	Number of molecules	11
	Total formula weight	1889.9
All*	Total formula weight	337703.9

*Water molecules are not included.