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6TVS

Crystal structure of the haemagglutinin mutant (Gln226Leu) from an H10N7 seal influenza virus isolated in Germany in complex with avian receptor analogue 3'-SLN

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E
(C, E, K)
Hemagglutinin HA1polymer32535484.13UniProt (A0A0A7HR51)
Pfam (PF00509)
Influenza A virus (A/harbour seal/Germany/1/2014(H10N7))
2B, D, F
(D, F, L)
Hemagglutinin HA2polymer17720313.43UniProt (A0A0A7HR51)
Pfam (PF00509)
Influenza A virus (A/harbour seal/Germany/1/2014(H10N7))
3G, I
(A, G)
N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranosebranched471.42In PDB
GlyTouCan (G30207PZ)
4H
(B)
N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched674.61In PDB
BIRD (PRD_900067)
GlyTouCan (G00065MO)
3'-sialyl-N-acetyllactosamine
5AA, J, K, L, N...
(L, C, D, E, F...)
1,2-ETHANEDIOLnon-polymer62.113Chemie (EDO)
6M, Q, U, Z
(D, E, F, L)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
7Y
(K)
CALCIUM IONnon-polymer40.11Chemie (CA)
8BA, CA, DA, EA, FA...
(C, D, E, F, K...)
waterwater18.01153Chemie (HOH)
Sequence modifications
C, E, K: 3 - 325 (UniProt: A0A0A7HR51)
PDBExternal DatabaseDetails
Asp 1-expression tag
Pro 2-expression tag
D, F, L: 1 - 176 (UniProt: A0A0A7HR51)
PDBExternal DatabaseDetails
Lys 177-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight167392.5
BranchedNumber of molecules3
Total formula weight1617.4
Non-Polymers*Number of molecules18
Total formula weight1731.8
All*Total formula weight170741.7
*Water molecules are not included.

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PDB entries from 2024-11-06

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