6TVS
Crystal structure of the haemagglutinin mutant (Gln226Leu) from an H10N7 seal influenza virus isolated in Germany in complex with avian receptor analogue 3'-SLN
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E (C, E, K) | Hemagglutinin HA1 | polymer | 325 | 35484.1 | 3 | UniProt (A0A0A7HR51) Pfam (PF00509) | Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) | |
2 | B, D, F (D, F, L) | Hemagglutinin HA2 | polymer | 177 | 20313.4 | 3 | UniProt (A0A0A7HR51) Pfam (PF00509) | Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) | |
3 | G, I (A, G) | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose | branched | 471.4 | 2 | In PDB GlyTouCan (G30207PZ) | |||
4 | H (B) | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 674.6 | 1 | In PDB BIRD (PRD_900067) GlyTouCan (G00065MO) | 3'-sialyl-N-acetyllactosamine | ||
5 | AA, J, K, L, N... (L, C, D, E, F...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 13 | Chemie (EDO) | |||
6 | M, Q, U, Z (D, E, F, L) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
7 | Y (K) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
8 | BA, CA, DA, EA, FA... (C, D, E, F, K...) | water | water | 18.0 | 1153 | Chemie (HOH) |
Sequence modifications
C, E, K: 3 - 325 (UniProt: A0A0A7HR51)
D, F, L: 1 - 176 (UniProt: A0A0A7HR51)
PDB | External Database | Details |
---|---|---|
Asp 1 | - | expression tag |
Pro 2 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Lys 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 167392.5 | |
Branched | Number of molecules | 3 |
Total formula weight | 1617.4 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 1731.8 | |
All* | Total formula weight | 170741.7 |