6TVD

Crystal structure of the haemagglutinin from a H10N7 seal influenza virus isolated in Germany in complex with avian receptor analogue, 3'-SLN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (A, C, E, G, I...)	Hemagglutinin HA1	polymer	325	35499.1	6	UniProt (A0A0A7HR51) Pfam (PF00509)	Influenza A virus
2	B, D, F, H, J... (B, D, F, H, J...)	Hemagglutinin HA2	polymer	177	20313.4	6	UniProt (A0A0A7HR51) Pfam (PF00509)	Influenza A virus
3	M, N, P, R, V (M, N, P, R, V)	N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		674.6	5	In PDB BIRD (PRD_900067) GlyTouCan (G00065MO)		3'-sialyl-N-acetyllactosamine
4	O, Q, S, U, W (O, Q, S, U, W)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	5	In PDB GlyTouCan (G42666HT)
5	T (T)	N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose	branched		471.4	1	In PDB GlyTouCan (G30207PZ)
6	AA, BA, CA, DA, FA... (C, E, F, G, I...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	9	Chemie (NAG)
7	EA, HA, Y (H, K, A)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
8	JA, KA, LA, MA, NA... (A, B, C, D, E...)	water	water		18.0	155	Chemie (HOH)

Sequence modifications

A, C, E, G, I, K: 1 - 323 (UniProt: A0A0A7HR51)

PDB	External Database	Details
Asp -1	-	expression tag
Pro 0	-	expression tag
Gln 219	Leu 228	conflict

B, D, F, H, J, L: 1 - 176 (UniProt: A0A0A7HR51)

PDB	External Database	Details
Lys 177	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	334874.8
Branched	Number of molecules	11
	Total formula weight	5966.4
Non-Polymers*	Number of molecules	12
	Total formula weight	2111.1
All*	Total formula weight	342952.3

*Water molecules are not included.