6TTS

Crystal structure of the GGDEF domain of DgcB from Caulobacter crescentus in complex with c-di-GMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	GGDEF diguanylate cyclase DgcB	polymer	199	21449.9	2	UniProt (A0A0H3CAN8) Pfam (PF00990) In PDB	Caulobacter vibrioides (strain NA1000 / CB15N)
2	A, B	9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)	non-polymer		690.4	5	Chemie (C2E)
3	A, B	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
4		water	water		18.0	16	Chemie (HOH)

Sequence modifications

A, B: 176 - 353 (UniProt: A0A0H3CAN8)

PDB	External Database	Details
Met 155	-	initiating methionine
Gly 156	-	expression tag
Ser 157	-	expression tag
Ser 158	-	expression tag
His 159	-	expression tag
His 160	-	expression tag
His 161	-	expression tag
His 162	-	expression tag
His 163	-	expression tag
His 164	-	expression tag
Ser 165	-	expression tag
Ser 166	-	expression tag
Gly 167	-	expression tag
Leu 168	-	expression tag
Val 169	-	expression tag
Pro 170	-	expression tag
Arg 171	-	expression tag
Gly 172	-	expression tag
Ser 173	-	expression tag
His 174	-	expression tag
Met 175	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	42899.8
Non-Polymers*	Number of molecules	11
	Total formula weight	4028.4
All*	Total formula weight	46928.2

*Water molecules are not included.