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6TTK

Crystal structure of the kelch domain of human KLHL12 in complex with DVL1 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Kelch-like protein 12polymer30132905.94UniProt (Q53G59)
Pfam (PF01344)
Pfam (PF24681)
Homo sapiens (Human)CUL3-interacting protein 1,DKIR homolog,hDKIR
2E, F, G, H
(F, G, H, E)
DVL1polymer151424.64UniProt (by SIFTS) (O14640)Homo sapiens
3I, K, L, M
(A, B, C)
SODIUM IONnon-polymer23.04Chemie (NA)
4J
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
5N
(D)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6O, P, Q, R, S...
(A, B, C, D, F...)
waterwater18.0645Chemie (HOH)
Sequence modifications
A, B, C, D: 268 - 567 (UniProt: Q53G59)
PDBExternal DatabaseDetails
Ser 267-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight137322.0
Non-Polymers*Number of molecules6
Total formula weight189.5
All*Total formula weight137511.5
*Water molecules are not included.

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PDB entries from 2026-03-18

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