6TT2
The PH domain of Bruton's tyrosine kinase mutant R28C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Tyrosine-protein kinase BTK | polymer | 169 | 19929.0 | 2 | UniProt (Q06187) Pfam (PF00169) Pfam (PF00779) In PDB | Homo sapiens (Human) | Agammaglobulinemia tyrosine kinase,ATK,B-cell progenitor kinase,BPK,Bruton tyrosine kinase |
| 2 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | water | water | 18.0 | 243 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 170 (UniProt: Q06187)
| PDB | External Database | Details |
|---|---|---|
| Cys 28 | Arg 28 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 39857.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 179.4 | |
| All* | Total formula weight | 40037.4 |
