6TT0
Crystal structure of a potent and reversible dual binding site Acetylcholinesterase chiral inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Acetylcholinesterase | polymer | 572 | 65315.6 | 1 | UniProt (P04058) Pfam (PF00135) | Tetronarce californica (Pacific electric ray) | AChE |
| 2 | B (A) | (1~{R},3~{S})-~{N}-(6,7-dimethoxy-2-oxidanylidene-chromen-3-yl)-3-[(phenylmethyl)amino]cyclohexane-1-carboxamide | non-polymer | 436.5 | 1 | Chemie (N9T) | |||
| 3 | C, D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 4 | E (A) | water | water | 18.0 | 88 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 65315.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 878.9 | |
| All* | Total formula weight | 66194.5 |
