6TRQ
S.c. Scavenger Decapping Enzyme DcpS in complex with the capped RNA dinucleotide m7G-GU
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | m7GpppX diphosphatase | polymer | 345 | 40210.9 | 4 | UniProt (Q06151) Pfam (PF05652) Pfam (PF11969) | Saccharomyces cerevisiae S288C | DCS-1,Hint-related 7meGMP-directed hydrolase 1,Protein Dcs1p,Scavenger mRNA-decapping enzyme DcpS |
| 2 | E, F (E, F) | Capped RNA dinucleotide | polymer | 2 | 606.4 | 2 | synthetic construct | ||
| 3 | G, H (D) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | I, K (E, F) | PHOSPHONATE | non-polymer | 80.0 | 2 | Chemie (2PO) | |||
| 5 | J, L (E, F) | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE | non-polymer | 458.2 | 2 | Chemie (M7G) | |||
| 6 | M (C) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 8 - 350 (UniProt: Q06151)
| PDB | External Database | Details |
|---|---|---|
| Gly 6 | - | expression tag |
| Met 7 | - | expression tag |
| Asn 268 | His 268 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 162056.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1268.6 | |
| All* | Total formula weight | 163324.9 |
