6TQ2
N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 5-(4-(4-fluorophenyl)-1H-imidazol-5-yl)-1-methylpyridin-2(1H)-one
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AAA, BBB, CCC | Bromodomain-containing protein 2 | polymer | 155 | 18039.9 | 3 | UniProt (P25440) Pfam (PF00439) In PDB | Homo sapiens (Human) | O27.1.1,Really interesting new gene 3 protein |
2 | AAA, CCC | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
3 | AAA, BBB, CCC | 5-[5-(4-fluorophenyl)-1~{H}-imidazol-4-yl]-1-methyl-pyridin-2-one | non-polymer | 269.3 | 3 | Chemie (NUQ) | |||
4 | AAA | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
5 | water | water | 18.0 | 332 | Chemie (HOH) |
Sequence modifications
AAA, BBB, CCC: 67 - 200 (UniProt: P25440)
PDB | External Database | Details |
---|---|---|
Met 46 | - | initiating methionine |
Gly 47 | - | expression tag |
Ser 48 | - | expression tag |
Ser 49 | - | expression tag |
His 50 | - | expression tag |
His 51 | - | expression tag |
His 52 | - | expression tag |
His 53 | - | expression tag |
His 54 | - | expression tag |
His 55 | - | expression tag |
Ser 56 | - | expression tag |
Ser 57 | - | expression tag |
Gly 58 | - | expression tag |
Leu 59 | - | expression tag |
Val 60 | - | expression tag |
Pro 61 | - | expression tag |
Arg 62 | - | expression tag |
Gly 63 | - | expression tag |
Ser 64 | - | expression tag |
His 65 | - | expression tag |
Met 66 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 54119.8 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1254.1 | |
All* | Total formula weight | 55373.9 |