6TNC
X-RAY STRUCTURE OF MPS1 IN COMPLEX WITH COMPOUND 46
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dual specificity protein kinase TTK | polymer | 294 | 33850.7 | 1 | UniProt (P33981) Pfam (PF00069) In PDB | Homo sapiens (Human) | Phosphotyrosine picked threonine-protein kinase,PYT |
2 | A | N-cyclopropyl-4-{8-[(thiophen-2-ylmethyl)amino]imidazo[1,2-a]pyrazin-3-yl}benzamide | non-polymer | 389.5 | 1 | Chemie (O23) | |||
3 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
4 | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A: 515 - 806 (UniProt: P33981)
PDB | External Database | Details |
---|---|---|
Gly 513 | - | expression tag |
Ser 514 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33850.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 424.9 | |
All* | Total formula weight | 34275.7 |