6TNB
X-RAY STRUCTURE OF MPS1 IN COMPLEX WITH COMPOUND 41
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual specificity protein kinase TTK | polymer | 294 | 33850.7 | 1 | UniProt (P33981) Pfam (PF00069) | Homo sapiens (Human) | Phosphotyrosine picked threonine-protein kinase,PYT |
| 2 | B (A) | (2~{R})-2-(4-fluorophenyl)-~{N}-[4-[2-[(2-methoxy-4-methylsulfonyl-phenyl)amino]-[1,2,4]triazolo[1,5-a]pyridin-6-yl]phenyl]propanamide | non-polymer | 559.6 | 1 | Chemie (8QW) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
A: 515 - 806 (UniProt: P33981)
| PDB | External Database | Details |
|---|---|---|
| Gly 513 | - | expression tag |
| Ser 514 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33850.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 595.1 | |
| All* | Total formula weight | 34445.8 |
