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6TN9

X-RAY STRUCTURE OF MPS1 IN COMPLEX WITH COMPOUND 16

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dual specificity protein kinase TTKpolymer29433770.81UniProt (P33981)
Pfam (PF00069)
Homo sapiens (Human)Phosphotyrosine picked threonine-protein kinase,PYT
2B
(A)
[4-[[6-(3,5-dimethyl-4-oxidanyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]phenyl]-morpholin-4-yl-methanonenon-polymer443.51Chemie (NN5)
Sequence modifications
A: 515 - 806 (UniProt: P33981)
PDBExternal DatabaseDetails
Gly 513-expression tag
Ser 514-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33770.8
Non-Polymers*Number of molecules1
Total formula weight443.5
All*Total formula weight34214.3
*Water molecules are not included.

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PDB entries from 2025-12-10

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