6TML

Cryo-EM structure of Toxoplasma gondii mitochondrial ATP synthase hexamer, composite model

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	q7, Q7, q8, Q8, q9...	ATPTG11	polymer	134	15425.4	6	UniProt (A0A125YPS4) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
2	i7, I7, i8, I8, i9...	ATPTG7	polymer	236	26866.8	6	UniProt (S7VXW3) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
3	t7, T7, t8, T8, t9...	ATPTG14	polymer	133	14424.5	6	UniProt (A0A125YLH9) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
4	g7, G7, g8, G8, g9...	ATPTG5	polymer	252	28162.6	6	UniProt (S7WD71) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
5	o7, O7, o8, O8, o9...	subunit k	polymer	157	17963.5	6	UniProt (A0A125YTD7) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
6	k7, K7, k8, K8, k9...	subunit a	polymer	224	24562.6	6	UniProt (A0A125YSI9) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
7	j7, J7, j8, J8, j9...	subunit i/j	polymer	229	26600.5	6	UniProt (S7UQ82) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
8	s7, S7, s8, S8, s9...	ATPTG13	polymer	128	14923.2	6	UniProt (A0A125YLN4) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
9	u7, U7, u8, U8, u9...	ATPTG15	polymer	126	13871.9	6	UniProt (A0A125YRP0) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
10	h7, H7, h8, H8, h9...	ATPTG6	polymer	239	27477.5	6	UniProt (A0A125YL08) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
11	e7, E7, e8, E8, e9...	ATPTG3	polymer	325	35159.2	6	UniProt (A0A125YLR0) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
12	x7, X7, x8, X8, x9...	ATPTG17,ATPTG17,ATPTG17	polymer	83	9486.7	6	UniProt (S7W180) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
13	b7, B7, b8, B8, b9...	subunit b	polymer	571	64811.6	6	UniProt (S7V2T0) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
14	r7, R7, r8, R8, r9...	ATPTG12	polymer	134	15400.6	6	UniProt (A0A125YKF7) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
15	p7, P7, p8, P8, p9...	ATPTG10	polymer	138	15165.2	6	UniProt (A0A125YMA7) Pfam (PF20716) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
16	v7, V7, v8, V8, v9...	subunit f	polymer	111	13030.0	6	UniProt (S7UQT7) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
17	l7, L7, l8, L8, l9...	ATPTG8	polymer	208	23365.9	6	UniProt (S7W7F1) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
18	c7, C7, c8, C8, c9...	ATPTG1	polymer	398	46025.4	6	UniProt (S7W9J5) Pfam (PF02167) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
19	d7, D7, d8, D8, d9...	ATPTG2	polymer	310	35238.5	6	UniProt (A0A125YV76) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
20	m7, M7, m8, M8, m9...	subunit 8	polymer	205	22344.6	6	UniProt (A0A125YPQ4) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
21	n7, N7, n8, N8, n9...	ATPTG9	polymer	166	18426.8	6	UniProt (A0A125YUZ2) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
22	f7, F7, f8, F8, f9...	ATPTG4	polymer	267	28557.4	6	UniProt (S7UVZ7) Pfam (PF00085) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
23	w7, W7, w8, W8, w9...	ATPTG16	polymer	106	11587.4	6	UniProt (S7VTI0) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
24	a7, A7, a8, A8, a9...	subunit d	polymer	536	61362.3	6	UniProt (S7V493) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
25	G1, G2, G3, G4, G5...	Oligomycin sensitivity conferring protein (OSCP)	polymer	252	27670.0	6	UniProt (A0A125YKF8) Pfam (PF00213) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
26	i1, i2, i3, i4, i5...	Inhibitor of F1	polymer	145	16167.5	6	UniProt (A0A125YJP2) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
27	A1, E1, C1, A2, E2...	ATP synthase subunit alpha	polymer	565	61189.2	18	UniProt (S7UU80) Pfam (PF02874) Pfam (PF00006) Pfam (PF00306) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
28	B1, F1, D1, B2, F2...	ATP synthase subunit beta	polymer	560	59983.3	18	UniProt (A0A125YYY4) Pfam (PF02874) Pfam (PF00006) Pfam (PF22919) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
29	g1, g2, g3, g4, g5...	ATP synthase subunit gamma	polymer	314	34573.0	6	UniProt (A0A125YUH0) Pfam (PF00231) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
30	d1, d2, d3, d4, d5...	ATP synthase subunit delta	polymer	183	19476.1	6	UniProt (A0A125YRE2) Pfam (PF02823) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
31	e1, e2, e3, e4, e5...	ATP synthase subunit epsilon	polymer	73	8492.7	6	UniProt (S7VV10) Pfam (PF04627) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)
32	H1, I1, J1, K1, L1...	subunit c	polymer	166	17753.5	60	UniProt (A0A125YJV2) Pfam (PF00137) In PDB	Toxoplasma gondii (strain ATCC 50853 / GT1)

Sequence modifications

g7, G7, g8, G8, g9, G9: 1 - 252 (UniProt: S7WD71)

PDB	External Database	Details
Val 51	Phe 51	conflict
Cys 73	Ser 73	conflict
Lys 110	Glu 110	conflict
Thr 233	Met 233	conflict

h7, H7, h8, H8, h9, H9: 1 - 239 (UniProt: A0A125YL08)

PDB	External Database	Details
Asn 89	His 89	conflict

e7, E7, e8, E8, e9, E9: 1 - 325 (UniProt: A0A125YLR0)

PDB	External Database	Details
-	Lys 14	deletion
Pro 63	Ser 64	conflict
Leu 99	Pro 100	conflict
Ala 312	Thr 313	conflict

x7, X7, x8, X8, x9, X9: 1 - 76 (UniProt: S7W180)
x7, X7, x8, X8, x9, X9: 77 - 83 (PDB: 6TML)
b7, B7, b8, B8, b9, B9: 3 - 573 (UniProt: S7V2T0)

PDB	External Database	Details
Leu 50	Ser 48	conflict
Thr 474	Ala 472	conflict

v7, V7, v8, V8, v9, V9: 1 - 111 (UniProt: S7UQT7)

PDB	External Database	Details
Ala 54	Val 54	conflict

n7, N7, n8, N8, n9, N9: 1 - 166 (UniProt: A0A125YUZ2)

PDB	External Database	Details
Ser 140	Ala 140	conflict

a7, A7, a8, A8, a9, A9: 1 - 536 (UniProt: S7V493)

PDB	External Database	Details
Thr 351	Ala 484	conflict

A1, E1, C1, A2, E2, C2, A3, E3, C3, A4, E4, C4, A5, E5, C5, A6, E6, C6: 1 - 538 (UniProt: S7UU80)
A1, E1, C1, A2, E2, C2, A3, E3, C3, A4, E4, C4, A5, E5, C5, A6, E6, C6: 539 - 565 (PDB: 6TML)

Contents of the asymmetric unit

Polymers	Number of chains	270
	Total formula weight	7546031.6
All*	Total formula weight	7546031.6

*Water molecules are not included.