6TML
Cryo-EM structure of Toxoplasma gondii mitochondrial ATP synthase hexamer, composite model
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, KD, MC, WG, Y... (q7, Q7, q8, Q8, q9...) | ATPTG11 | polymer | 134 | 15425.4 | 6 | UniProt (A0A125YPS4) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 2 | B, LD, NC, XG, Z... (i7, I7, i8, I8, i9...) | ATPTG7 | polymer | 236 | 26866.8 | 6 | UniProt (S7VXW3) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 3 | AA, AG, C, MD, OC... (t7, T7, t8, T8, t9...) | ATPTG14 | polymer | 133 | 14424.5 | 6 | UniProt (A0A125YLH9) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 4 | BA, BG, D, ND, PC... (g7, G7, g8, G8, g9...) | ATPTG5 | polymer | 252 | 28162.6 | 6 | UniProt (S7WD71) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 5 | AH, CA, CG, E, OD... (o7, O7, o8, O8, o9...) | subunit k | polymer | 157 | 17963.5 | 6 | UniProt (A0A125YTD7) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 6 | BH, DA, DG, F, PD... (k7, K7, k8, K8, k9...) | subunit a | polymer | 224 | 24562.6 | 6 | UniProt (A0A125YSI9) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 7 | CH, EA, EG, G, QD... (j7, J7, j8, J8, j9...) | subunit i/j | polymer | 229 | 26600.5 | 6 | UniProt (S7UQ82) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 8 | DH, FA, FG, H, RD... (s7, S7, s8, S8, s9...) | ATPTG13 | polymer | 128 | 14923.2 | 6 | UniProt (A0A125YLN4) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 9 | EH, GA, GG, I, SD... (u7, U7, u8, U8, u9...) | ATPTG15 | polymer | 126 | 13871.9 | 6 | UniProt (A0A125YRP0) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 10 | FH, HA, HG, J, TD... (h7, H7, h8, H8, h9...) | ATPTG6 | polymer | 239 | 27477.5 | 6 | UniProt (A0A125YL08) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 11 | GH, IA, IG, K, UD... (e7, E7, e8, E8, e9...) | ATPTG3 | polymer | 325 | 35159.2 | 6 | UniProt (A0A125YLR0) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 12 | HH, JA, JG, L, VD... (x7, X7, x8, X8, x9...) | ATPTG17,ATPTG17,ATPTG17 | polymer | 83 | 9486.7 | 6 | UniProt (S7W180) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 13 | IH, KA, KG, M, WD... (b7, B7, b8, B8, b9...) | subunit b | polymer | 571 | 64811.6 | 6 | UniProt (S7V2T0) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 14 | JH, LA, LG, N, XD... (r7, R7, r8, R8, r9...) | ATPTG12 | polymer | 134 | 15400.6 | 6 | UniProt (A0A125YKF7) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 15 | AD, KH, MA, MG, O... (p7, P7, p8, P8, p9...) | ATPTG10 | polymer | 138 | 15165.2 | 6 | UniProt (A0A125YMA7) Pfam (PF20716) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 16 | BD, LH, NA, NG, P... (v7, V7, v8, V8, v9...) | subunit f | polymer | 111 | 13030.0 | 6 | UniProt (S7UQT7) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 17 | AE, CD, MH, OA, OG... (l7, L7, l8, L8, l9...) | ATPTG8 | polymer | 208 | 23365.9 | 6 | UniProt (S7W7F1) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 18 | BE, DD, NH, PA, PG... (c7, C7, c8, C8, c9...) | ATPTG1 | polymer | 398 | 46025.4 | 6 | UniProt (S7W9J5) Pfam (PF02167) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 19 | CE, ED, OH, QA, QG... (d7, D7, d8, D8, d9...) | ATPTG2 | polymer | 310 | 35238.5 | 6 | UniProt (A0A125YV76) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 20 | DE, FD, PH, RA, RG... (m7, M7, m8, M8, m9...) | subunit 8 | polymer | 205 | 22344.6 | 6 | UniProt (A0A125YPQ4) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 21 | EE, GD, QH, SA, SG... (n7, N7, n8, N8, n9...) | ATPTG9 | polymer | 166 | 18426.8 | 6 | UniProt (A0A125YUZ2) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 22 | FE, HD, RH, TA, TG... (f7, F7, f8, F8, f9...) | ATPTG4 | polymer | 267 | 28557.4 | 6 | UniProt (S7UVZ7) Pfam (PF00085) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 23 | GE, ID, SH, UA, UG... (w7, W7, w8, W8, w9...) | ATPTG16 | polymer | 106 | 11587.4 | 6 | UniProt (S7VTI0) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 24 | HE, JD, TH, VA, VG... (a7, A7, a8, A8, a9...) | subunit d | polymer | 536 | 61362.3 | 6 | UniProt (S7V493) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 25 | IE, JE, UH, VH, WA... (G1, G2, G3, G4, G5...) | Oligomycin sensitivity conferring protein (OSCP) | polymer | 252 | 27670.0 | 6 | UniProt (A0A125YKF8) Pfam (PF00213) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 26 | EF, KE, QI, SB, WH... (i1, i2, i3, i4, i5...) | Inhibitor of F1 | polymer | 145 | 16167.5 | 6 | UniProt (A0A125YJP2) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 27 | AB, BB, FF, GF, HF... (A1, E1, C1, A2, E2...) | ATP synthase subunit alpha | polymer | 565 | 61189.2 | 18 | UniProt (S7UU80) Pfam (PF02874) Pfam (PF00006) Pfam (PF00306) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 28 | AI, BI, CB, CI, DB... (B1, F1, D1, B2, F2...) | ATP synthase subunit beta | polymer | 560 | 59983.3 | 18 | UniProt (A0A125YYY4) Pfam (PF02874) Pfam (PF00006) Pfam (PF22919) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 29 | DI, FB, LF, RE, XI... (g1, g2, g3, g4, g5...) | ATP synthase subunit gamma | polymer | 314 | 34573.0 | 6 | UniProt (A0A125YUH0) Pfam (PF00231) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 30 | AC, EI, GB, MF, SE... (d1, d2, d3, d4, d5...) | ATP synthase subunit delta | polymer | 183 | 19476.1 | 6 | UniProt (A0A125YRE2) Pfam (PF02823) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 31 | BC, FI, HB, NF, TE... (e1, e2, e3, e4, e5...) | ATP synthase subunit epsilon | polymer | 73 | 8492.7 | 6 | UniProt (S7VV10) Pfam (PF04627) | Toxoplasma gondii (strain ATCC 50853 / GT1) | |
| 32 | AF, AJ, BF, BJ, CC... (H1, I1, J1, K1, L1...) | subunit c | polymer | 166 | 17753.5 | 60 | UniProt (A0A125YJV2) Pfam (PF00137) | Toxoplasma gondii (strain ATCC 50853 / GT1) |
Sequence modifications
g7, G7, g8, G8, g9, G9: 1 - 252 (UniProt: S7WD71)
h7, H7, h8, H8, h9, H9: 1 - 239 (UniProt: A0A125YL08)
e7, E7, e8, E8, e9, E9: 1 - 325 (UniProt: A0A125YLR0)
x7, X7, x8, X8, x9, X9: 1 - 76 (UniProt: S7W180)
x7, X7, x8, X8, x9, X9: 77 - 83 (PDB: 6TML)
b7, B7, b8, B8, b9, B9: 3 - 573 (UniProt: S7V2T0)
v7, V7, v8, V8, v9, V9: 1 - 111 (UniProt: S7UQT7)
n7, N7, n8, N8, n9, N9: 1 - 166 (UniProt: A0A125YUZ2)
a7, A7, a8, A8, a9, A9: 1 - 536 (UniProt: S7V493)
A1, E1, C1, A2, E2, C2, A3, E3, C3, A4, E4, C4, A5, E5, C5, A6, E6, C6: 1 - 538 (UniProt: S7UU80)
A1, E1, C1, A2, E2, C2, A3, E3, C3, A4, E4, C4, A5, E5, C5, A6, E6, C6: 539 - 565 (PDB: 6TML)
| PDB | External Database | Details |
|---|---|---|
| Val 51 | Phe 51 | conflict |
| Cys 73 | Ser 73 | conflict |
| Lys 110 | Glu 110 | conflict |
| Thr 233 | Met 233 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Asn 89 | His 89 | conflict |
| PDB | External Database | Details |
|---|---|---|
| - | Lys 14 | deletion |
| Pro 63 | Ser 64 | conflict |
| Leu 99 | Pro 100 | conflict |
| Ala 312 | Thr 313 | conflict |
x7, X7, x8, X8, x9, X9: 77 - 83 (PDB: 6TML)
b7, B7, b8, B8, b9, B9: 3 - 573 (UniProt: S7V2T0)
| PDB | External Database | Details |
|---|---|---|
| Leu 50 | Ser 48 | conflict |
| Thr 474 | Ala 472 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 54 | Val 54 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 140 | Ala 140 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Thr 351 | Ala 484 | conflict |
A1, E1, C1, A2, E2, C2, A3, E3, C3, A4, E4, C4, A5, E5, C5, A6, E6, C6: 539 - 565 (PDB: 6TML)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 270 |
| Total formula weight | 7546031.6 | |
| All* | Total formula weight | 7546031.6 |
